Consider a biologic for active ankylosing spondylitis (AS) treatment

Living with ankylosing spondylitis can feel like an ongoing challenge

You've probably been managing your ankylosing spondylitis (AS) for a while now. Are you getting less relief from your current medicine? Over time, the joints and bones of the spine can grow together, or fuse. This may cause the spine to become rigid and inflexible. There are treatments that may help improve the symptoms of active AS. So talk to your doctor if you notice symptoms getting worse. They can help you find a treatment that’s right for you.

Anti-TNF biologics may help control the symptoms of active ankylosing spondylitis

Tumor necrosis factor-alpha, or TNF-alpha, is a substance in the body that causes inflammation. In people with AS, too much TNF can cause the immune system to attack parts of the body. This can lead to symptoms of pain and stiffness experienced by patients with AS.

Anti-TNF biologics are a type of medicine that can be used to help treat active AS by reducing back pain and stiffness.

It’s important to know that blocking too much TNF-alpha can lessen your body’s ability to fight infections.

Anti-TNF biologics are a type of medicine that can be used to treat active AS by reducing back pain and stiffness.

Deciding to start a biologic can be an important decision

When your current treatment isn’t enough to help control your AS symptoms, it may be time to consider a biologic, such as SIMPONI ARIA®. Deciding to start on a biologic is an important decision, and there is a lot to learn. By learning more about biologics, you can be better prepared to to speak with your doctor and make a shared decision.

How biologics are given

Once you and your doctor make the decision to start a biologic, 
you will discuss and decide how to take your medication.

Some biologics, such as SIMPONI ARIA®, are given as an infusion. 
Infusion biologics are prepared and given by a healthcare professional through a needle placed in your vein, usually in your arm.

Other biologics are given as a self-injection. 
Self-injection biologics are given by yourself or a caregiver after proper training by your healthcare professional.

The information below can help you understand some considerations for infusions and self-injections so that you can discuss with your doctor which one is right for you.

Learn about some considerations for infusions or self-injections 
in the treatment of active AS

Infusions

Self-injections

Where is the medicine given?

  • At your doctor’s office
  • If your doctor’s office does not provide infusions, you may go to a local infusion center or hospital
  • At home

Who gives the medicine?

  • A healthcare professional, like a doctor or nurse
  • Yourself or a caregiver
  • You will need proper training from your doctor before you can start giving yourself injections

How is the medicine given?

  • Given through a needle placed in your vein, usually in your arm (infusion)
  • Given as an injection (using a needle) under the skin (subcutaneous injection). The treatment usually comes in an injection device (prefilled with the medication)

How often will you receive the medicine?

  • How often you receive the medicine varies depending on the medication
  • How often you receive the medicine varies depending on the medication

Who will manage getting the medicine?

  • Your doctor’s office will manage getting the medicine in time for your next infusion appointment
  • You will need to fill your prescription in a timely manner and have it delivered to your home

Who will manage storing the medicine?

  • Your doctor’s office will manage storing the medicine properly and keeping it refrigerated
  • You will need to store the medicine properly by keeping it refrigerated

Who will manage disposing of the medicine?

  • Your doctor’s office will manage disposing of the medicine properly
  • You will need to dispose of your medicine properly, per local regulations

There are additional important considerations for selecting a treatment. Talk to your doctor about treatment options and what may be right for you.