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Learn About SIMPONI ARIA® (golimumab) | SIMPONI ARIA®
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Ask your doctor today if SIMPONI ARIA® may be right for you.

SIMPONI ARIA® was evaluated in medical studies for joint symptoms, functional health, well-being and fatigue. See our results below.

SIMPONI ARIA® is a prescription medication used to treat moderate to severe rheumatoid arthritis (RA) in adults, used in combination with methotrexate; active psoriatic arthritis (PsA) in people 2 years of age and older; active ankylosing spondylitis (AS) in adults and active polyarticular juvenile idiopathic arthritis (pJIA) in people 2 years of age or older.

 

RESULTS WITH SIMPONI ARIA® IN ADULT PATIENTS

Please select a condition to learn more about SIMPONI ARIA® results in medical studies.

In a medical study of 395... See More patients with RA, 59% of patients treated with SIMPONI ARIA® when taken with methotrexate (MTX) had a 20% improvement in symptoms of RA (joint pain, stiffness, and swelling) at 14 weeks, compared to 25% of the 197 patients treated with MTX alone.

71% of 395 patients treated with... See More SIMPONI ARIA® when taken with MTX had no further joint damage as seen on X-ray at 24 weeks, compared to 57% of the 197 patients treated with MTX alone. SIMPONI ARIA® when taken with MTX may allow you to do the things you need to do with less difficulty.

In a medical study, some ... See Morepatients treated with SIMPONI ARIA® when taken with MTX showed improvement in both physical and emotional well-being, compared to patients treated with MTX alone, as measured by a general health assessment that includes these 8 areas:
PHYSICAL WELL-BEING
Physical Functioning: Limitations in performing physical activities
Role Limitations (Physical): Physical challenges that limit your daily activities
Body Pain: General body pain experienced
General Health: How you feel about your overall health
EMOTIONAL WELL-BEING
Social Limitations: Any effects that physical or emotional health problems have on your social life
Role Limitations (Emotional): Emotional challenges that limit your daily activities
Energy and Fatigue: The energy or fatigue that you experience
General Emotional Health: How you feel, emotionally, most of the time

Treatment with SIMPONI... See More ARIA® when taken with MTX resulted in improvement in fatigue in some patients. In a medical study, the level of fatigue was assessed using a questionnaire to measure self-reported tiredness, weakness, and difficulty conducting usual activities due to fatigue. Patients were asked to indicate their level of fatigue in the 7 days prior.

Individual results may vary.

In a medical study, 75% of... See More 241 patients treated with SIMPONI ARIA® had a 20% improvement in symptoms of PsA (joint pain, stiffness, and swelling) at 14 weeks, compared to 22% of 239 patients treated with placebo.

59% of 196 patients treated with... See More SIMPONI ARIA® had 75% improvement in skin symptoms of PsA (plaque thickness, redness, and scaling) at 14 weeks, compared to 14% of 198 patients treated with placebo. SIMPONI ARIA® has not been studied in and is not approved for plaque psoriasis.

72% of 237 patients treated with... See More SIMPONI ARIA® had no further joint damage as seen on X-ray at 24 weeks, compared to 43% of 237 patients treated with placebo. SIMPONI ARIA® may allow you to do the things you need to do with less difficulty.

In a medical study, some ... See Morepatients treated with SIMPONI ARIA® showed improvement in both physical and emotional well-being, compared to patients treated with placebo, as measured by a general health assessment that includes these 8 areas:
PHYSICAL WELL-BEING
Physical Functioning: Limitations in performing physical activities
Role Limitations (Physical): Physical challenges that limit your daily activities
Body Pain: General body pain experienced
General Health: How you feel about your overall health
EMOTIONAL WELL-BEING
Social Limitations: Any effects that physical or emotional health problems have on your social life
Role Limitations (Emotional): Emotional challenges that limit your daily activities
Energy and Fatigue: The energy or fatigue that you experience
General Emotional Health: How you feel, emotionally, most of the time

Treatment with SIMPONI... See More ARIA® resulted in improvement in fatigue in some patients. In a medical study, the level of fatigue was assessed using a questionnaire to measure self-reported tiredness, weakness, and difficulty conducting usual activities due to fatigue. Patients were asked to indicate their level of fatigue in the 7 days prior.

Individual results may vary.

In a medical study, SIMPONI... See More ARIA® was proven to reduce the symptoms of active AS, including back pain and morning stiffness. 73% of 105 patients treated with SIMPONI ARIA® noticed a 20% improvement at 16 weeks, compared to 26% of 103 patients treated with placebo. SIMPONI ARIA® has been shown to help improve spine mobility/range of motion in patients with AS.

In a medical study, some ... See Morepatients treated with SIMPONI ARIA® showed improvement in both physical and emotional well-being, compared to patients treated with placebo, as measured by a general health assessment that includes these 8 areas:
PHYSICAL WELL-BEING
Physical Functioning: Limitations in performing physical activities
Role Limitations (Physical): Physical challenges that limit your daily activities
Body Pain: General body pain experienced
General Health: How you feel about your overall health
EMOTIONAL WELL-BEING
Social Limitations: Any effects that physical or emotional health problems have on your social life
Role Limitations (Emotional): Emotional challenges that limit your daily activities
Energy and Fatigue: The energy or fatigue that you experience
General Emotional Health: How you feel, emotionally, most of the time

Individual results may vary.

Individual results may vary.

30-MINUTE INFUSION? LEARN MORE, RIGHT THIS WAY.

SIMPONI ARIA® is a biologic treatment given by intravenous infusion, also known as an IV. Your treatment starts with a 30-minute infusion, followed by a second 30-minute infusion 4 weeks later. Then you’ll receive your infusions every 8 weeks—that’s as few as 6 times a year. The infusion is given through a needle placed in your vein, usually in your arm.

See the path to your first infusion, step by step

SERIOUS AND COMMON SIDE EFFECTS WITH SIMPONI ARIA®

Serious side effects

SIMPONI ARIA® (golimumab) can lower your ability to fight infections. Serious and sometimes fatal events may occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Other possible serious side effects may include lymphoma, a rare and fatal cancer called hepatosplenic T-cell lymphoma, skin cancer, other cancers, hepatitis B, heart failure, nervous system problems, lupus-like symptoms, or allergic reactions.

To learn more about these and other risks, please read the Important Safety Information and Medication Guide for SIMPONI ARIA®, and talk with your doctor.

Common side effects

The most common side effects of SIMPONI ARIA® include:

  • upper respiratory infection (runny nose, sore throat, and hoarseness or laryngitis)
  • abnormal liver tests
  • decreased blood cells that fight infection
  • viral infections, such as flu and cold sores in the mouth
  • bronchitis
  • high blood pressure
  • rash

To learn more about these and other risks, please read the Important Safety Information and Medication Guide for SIMPONI ARIA®, and talk with your doctor.

Read Important Safety Information

DISCUSSING SIMPONI ARIA® WITH YOUR DOCTOR

The only way to find out if SIMPONI ARIA® is right for you is to have an open and honest conversation with your doctor about the symptoms you’re experiencing.

If you’d like some help getting that talk started, choose one of the discussion guides below:

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ABOUT SIMPONI ARIA®?

If you’d like to learn more about SIMPONI ARIA®, you can download our brochure here.

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30-Minute Infusion? Learn More, Right This Way.