Stay in control of your schedule

A short infusion helps you plan your day

The following table provides important information about SIMPONI ARIA® to help you talk to your doctor and decide if this biologic may be right for you.


Where is SIMPONI ARIA® given?

  • At your doctor’s office
  • If your doctor’s office does not provide infusions, you may go to a local infusion center or hospital

Who gives SIMPONI ARIA®?

  • A healthcare professional, like a doctor or nurse
  • He/she will check your vital signs and health, provide you with the Medication Guide to read before each infusion, and monitor you during and after treatment

How is SIMPONI ARIA® given?

  • Through a needle placed in your vein, usually in your arm
  • The amount of medication for each dose is based on your weight
  • Taken with methotrexate for rheumatoid arthritis (RA) or with or without methotrexate for psoriatic arthritis (PsA) and ankylosing spondylitis (AS), as directed

How often is SIMPONI ARIA® given?

  • A short 30-minute infusion is given as 2 starter doses 4 weeks apart. Then you will receive infusions every 8 weeks—that’s as few as 6 times a year

Who will manage getting SIMPONI ARIA®?

  • Your doctor’s office will manage getting SIMPONI ARIA® in time for your next infusion appointment

Who will manage storing SIMPONI ARIA®?

  • Your doctor’s office will manage storing SIMPONI ARIA® properly

Who will manage disposing of SIMPONI ARIA®?

  • Your doctor’s office will manage disposing of SIMPONI ARIA® properly

SIMPONI ARIA® is an anti-TNF biologic infusion for adults with:

  • Moderate to severe rheumatoid arthritis, used in combination with methotrexate. Methotrexate is taken as directed
  • Active psoriatic arthritis
  • Active ankylosing spondylitis

Your doctor should test you for tuberculosis (TB) and hepatitis B before starting SIMPONI ARIA® and monitor you closely for signs and symptoms of TB during treatment. You should not receive SIMPONI ARIA® if you have an infection unless your doctor says it is okay.

Customized weight-based dosing with SIMPONI ARIA®

SIMPONI ARIA® offers customized dosing based on your weight. Before every treatment, a healthcare professional will carefully calculate the right dose for you.

Watch the SIMPONI ARIA® infusion video

After talking with your doctor, you may still have questions about receiving an infusion. This video walks you through the steps for the SIMPONI ARIA® infusion process—before, during, and after treatment—and explains what to expect during the infusion.

This video discusses use in RA only. While dosing with methotrexate varies by condition, the dosing and administration for SIMPONI ARIA® applies to all conditions.

View this helpful checklist for tips and information to help you prepare for your infusion with SIMPONI ARIA®

The day of your treatment

Before your appointment, be ready to share your medical history and a list of medicines you are taking. If any medicines have changed, let your healthcare professional know that too. It's also important to eat a healthy meal beforehand.

When you arrive for your treatment, a healthcare professional will perform an assessment of your health and check your blood pressure, heart rate, temperature, and weight. Before each infusion, your doctor will calculate the right amount of SIMPONI ARIA® medication for you, based on your weight, and will prepare your infusion. A nurse will provide you with the Medication Guide for SIMPONI ARIA® to read before each infusion. Talk to your healthcare professional about any questions.

SIMPONI ARIA® is given through a needle placed in your vein. This is called an infusion. It is usually given in your arm. The infusion will take 30 minutes. A healthcare professional will monitor you during the infusion and for a period of time afterward. If you have questions or experience side effects during or after your infusion, discuss them with the healthcare professional overseeing your treatment.

After your infusions, if you experience any side effects, call your doctor right away. If you forget or miss an infusion appointment, make another appointment as soon as possible.

Please read the full Prescribing Information including Boxed Warnings, and Medication Guide for SIMPONI ARIA®, and discuss any questions with your doctor.